Abstract
T he expression of cell function is depended upon the activity of mitochondria. The key of evolution has depended upon the number and shape of mitochondria is actively working in the differentiated cell by the observation of bio-imaging method because differentiated function depends upon mitochondria job. On the processing of carcinogenesis mitochondria respiratory dysfunction has inevitably appeared. To avoid cancer suffering, it is necessary for human-being to protect mitochondrial function. Nuclear DNA was covered by double membrane, but mitochondria DNA has not covered by membrane, naked DNA. So, carcinogen, radiation, ultraviolet can easily damage mitochondria DNA 10 times more fragile than nuclear DNA. Human being has named some hundreds of bacteria, but we are letting our lives by 1000 trillion intestinal bacteria, human body has constituted from 60 trillion cells, so this population is only under 1% compared with them. Furthermore, our higher animal cell is sponsored from 1~2000 α-proteo-bacteria. This means that higher animal cell is sponsored by many of original bacteria. So, our life is the matrix among bacteria which let our higher animal cell live along. Joshua Lederberg, novel prize (science, 228, 287, 2000) 1 have proposed that host and co-existing microbiota are collective body which are complicated with many gene information. So, we should think “super-organism” and we don’t think that microbiota is bad fellow but think that the mutual relationship between host and normal flora which constitute this super-organism. In the colon canal, 1000 trillion intestinal bacteria exist. Professor Ito has verified that colon cannot keep colon shape without 46 stuck of clostridium by the comparative experiment of disinfected mouse 2. So, clostridium is inevitable necessary for co-existing bacteria. Third problem: When we consider why 1000 trillion intestinal bacteria live in the intestinal canal and why intestinal bacteria flora of mother and children are the same, we must consider that human development is derived from miniature of live earth, so we must think that original anaerobic earth circumstances are inherited in the colon.
Citation
Kumar S. Correlation between Body and Bacteria. SM J Dent. 2018; 4(1): 1020s.