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SM Journal of Pediatrics

A Case of Reverse Shapiro Syndrome Responding to Cyprohepatadine

[ ISSN : 3067-9990 ]

Abstract
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Received: 21-Aug-2017

Accepted: 13-Sep-2017

Published: 20-Sep-2017

Case Report | Volume 2 - Issue 2 | Article DOI :

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Hicham Mansour*, Maha Sabouneh and Ghassan Hmaimess

Department of Pediatrics, Saint George University Medical Center, Balamand University, Lebanon

Corresponding Author:

Hicham Mansour, Department of Pediatrics, Lebanon, Tel: 009613374216;

Keywords

Reverse Shapiro syndrome; West syndrome; Corpus callosum agenesis; Hyperthermia

Abstract

Reverse Shapiro syndrome consists of the association of unexplained hyperthermia and corpus callosum agenesis. The genetic basis is still unidentified; yet, neurochemical abnormalities as well as hypothalamic dysfunction have been proposed as possible etiologies. Only four cases of reverse Shapiro Syndrome have been reported to date and many therapeutic managements have been proposed without any radical success. Here we report a new case of a 6 months old male patient, with controlled cryptogenic epilepsy who is also presenting with a reverse Shapiro syndrome. The patient presented with recurrent episodes of hyperthermia that responded completely to a treatment by cyproheptadine.

Citation

Mansour H, Sabouneh M and Hmaimess G. A Case of Reverse Shapiro Syndrome Responding to Cyprohepatadine. SM J Pediatr. 2017; 2(2): 1010