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Annals of Environmental Science and Ecology

Evaluating Changes in Contaminants of Emerging Concern in Municipal Wastewater Effluents Following Treatment Plant Upgrades

Abstract
Details

Received: 09-Jun-2025

Accepted: 08-Aug-2025

Published: 09-Aug-2025

Nivetha Srikanthan1 , Azar Fattahi1*, E. Katie McCann1 , Leslie M. Bragg1 , Hadi Dhiyebi1 , Diana M. Cardenas-Soraca1 , Pam Law2 , Dominika Celmer-Repin2 , Sonya Kleywegt3 , Wayne J. Parker1 and Mark R. Servos1

1 University of Waterloo, Canada

2 Region of Waterloo, Canada

3 Ontario Ministry of the Environment, Canada

Corresponding Author:

Azar Fattahi, University of Waterloo, 200 University Ave W, Waterloo, ON, N2L 3G1, Canada.

Keywords

Municipal Wastewater Treatment Plant Effluent (WWTP); Chemicals of Emerging Concern (CECs); Hormones; Yeast Estrogen Screen (YES); Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS).

Abstract

Contaminants of emerging concern (CEC) are known to affect aquatic organisms downstream of wastewater treatment plant effluent discharges. Studies in the Grand River watershed on the small-bodied, benthic rainbow darter (Etheostoma caeruleum) have shown altered gene expression, sex steroid levels, gonad size and expression of intersex (testis-ova) associated with wastewater outfalls. Due to these observed biological impacts, over $450M has been spent by the municipal government to upgrade the two major wastewater treatment plants (WWTP) within the Grand River watershed (Waterloo, Kitchener). In this study we monitored process upgrades at each of the WWTPs between 2010 to 2019 for a suite of chemicals including nutrients, CECs, hormones and total estrogenicity. Effluent samples for select CECs and total estrogenicity were analyzed by LC-MS/MS and yeast estrogen screen (YES) assay, respectively. Estrogenicity of the effluent declined rapidly after upgrades were completed. The removal of key CECs varied depending on their physiochemical properties. Although treatment process upgrades lead to greatly reduced environmental exposure to many CECs such as naproxen, some remain at relatively high concentrations (i. e. carbamazepine) that may continue to represent a risk to the environment.

Citation

Srikanthan N, Fattahi A,McCann EK, Bragg LM, Dhiyebi H, et al. (2025) Evaluating Changes in Contaminants of Emerging Concern in Municipal Wastewater Ef