Keywords
Laparoscopic cholecystectomy; children, sickle cell disease
Abstract
Background: Aim of this study is to evaluate if there is any difference in terms of hemodynamic parameters during Laparoscopic Cholecystectomy (LC) in children with Sickle Cell Disease (SCD) and Non-Sickle Cell Disease (NSCD).
Methods: Twenty children with asymptomatic cholelithiasis, recruited for elective LC were allocated into two groups: group 1 (n: 10) children without SCD (control group), and group 2 (n: 10) children with SCD. All of the patients with SCD had preoperative hematological evaluation for the surgical procedure. Study parameters included: heart rate, mean blood pressure, Peak Inspiration Pressure (PIP), end-tidal carbon dioxide concentration (PETCO2), expiratory tidal volume (Vt), O2 saturation, arterial blood gases (pH, PaCO2, PaO2, HCO3), hematocrit and intra-abdominal pressures. Parameters were recorded at five moments: before CO2 insufflation, 15, 45, 60 minutes after insufflation in reverse Trendelenburg position and 5 minutes after CO2 insufflation in the supine position.
Results: Regarding all parameters, before and after CO2 insufflation and after CO2 insufflation, there were insignificant changes in each group and between the two groups. Intra-abdominal pressure changes did not affect the hemodynamic parameters. No postoperative complication was observed and the post-operative hospital stay in two groups was similar.
Conclusion: Although sample size is not enough this study reveal that laparoscopic cholecystectomy does not have any adverse effects on hemodynamic parameters of children with sickle cell disease. Laparoscopic cholecystectomy may be feasible and as safe as in NSCD patients.
Citation
Özden Ö, Alkan M, K?l?ç ?S and Hatipo?lu Z. Evaluation of Hemodynamic Parameters during Laparoscopic Cholecystectomyin Children with Sickle Cell Disease and Non-sickle Cell Disease. SM J Pediatr Surg. 2016; 2(5): 1028.