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IDH1 Mutations in Glioma: Considerations for Radiotracer Development

[ ISSN : 3067-9702 ]

Abstract

Editorial | Volume 2 - Issue 1 | Article DOI :

Satish K Chitneni

Department of Radiology, Duke University Medical Center, USA

Corresponding Author:

Satish K Chitneni, Department of Radiology, Duke University Medical Center, Durham, NC 27710, Box 3808, USA, Email: satish.chitneni@duke.edu

Keywords:

Abstract

Isocitrate dehydrogenases IDH1 and IDH2 are closely-related metabolic enzymes which catalyze the conversion of isocitrate to α-ketoglutarate (α-KG) by oxidative decarboxylation and simultaneously generate NADPH in cells

Citation

Chitneni SK. IDH1 Mutations in Glioma: Considerations for Radiotracer Development. SM J Radiol. 2016; 2(1): 1009.

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Received: 21-Mar-2016

Accepted: 23-Mar-2016

Published: 31-Mar-2016