Abstract
Aedes aegypti, a main vector of dengue fever, is very high density in some areas of Vietnam. These mosquitoes in some cities such as Hanoi (HN), Nhatrang (NT), Dongnai (DN), Kiengiang (KG), Daklak (DL), and Hochiminh (HCM) cities have been found high resistance to Pyrethroid group and DDT. Mosquito populations have been sensitive to malathion insecticide.
Identifying insecticide resistant characteristics by esterase enzyme electrophoresis showed that the first esterase appeared in pyrethroid insecticide resistant mosquito population and not recorded in Bora Bora strain.
Analysis of mutations in by multiplex PCR 1011 and 1016 codons encoding VAL and ISO in 20 and 21 exons showed that mutation in 1016 codons with two types VAL/1016/ISO and VAL/1016/GLY were found in the domain II of the sodium channel gene with 94 Aedes aegypti adult female mosquitoes after susceptibility test to alphacypermethrin. The results showed that no mutation in 1011 codon encoding ISO was observed. 14 samples collected from four provinces containing mutations in 1016 codons with two VAL/1016/ISO and VAL/1016/GLY types have been detected.
Citation
Thi KP, Viet HH and Nguyen HM. Major Resistant Mechanism to Insecticides of Aedes Aegypti Mosquito: a Vector of Dengue and Zika Virus in Vietnam. SM Trop Med J. 2016; 1(2): 1010.