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SM Journal of Pediatric Surgery

PDA Aneurysm in a Neonate with ACTA2 Mutation

[ ISSN : 2573-3419 ]

Abstract
Details

Received: 08-May-2018

Accepted: 24-May-2018

Published: 28-May-2018

Case Report | Volume 4 - Issue 3 | Article DOI :

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Pierpaolo Chivasso*, Robert Tulloh, Serban Stoica, and Ragini Pandey

Department of Congenital Heart Disease and Cardiac Surgery, University Hospitals Bristol NHS Foundation Trust, United Kingdom

Corresponding Author:

Pierpaolo Chivasso, University Hospitals Bristol NHS Foundation Trust, Upper Maudlin Street, BS2 8HW, Bristol, United Kingdom, Tel: 0044(0)1173423523; Email: pierpaolochivasso@icloud.com

Keywords

s ACTA 2 Mutation; PDA Aneurysm; Case Report; Congenital Heart Disease

Abstract

ACTA2 (actin, alpha 2, smooth muscle) mutation associated with PDA aneurysm rarely presents with heart failure in neonates. Survival is poor with impaired quality of life due to strokes, aneurysms and thromboticischemic events.

We describe a neonate with ACTA2 mutation found to have a 3 cm arterial duct aneurysm (PDA) extending into the distal arch and proximal main pulmonary artery (MPA) with impaired left ventricular systolic function. She underwent excision of the aneurysm and repair of distal arch under deep hypothermic circulatory arrest (DHCA) with good immediate outcome.

Citation

Chivasso P, Tulloh R, Stoica S and Pandey R. PDA Aneurysm in a Neonate with ACTA 2 Mutation. SM J Pediatr Surg. 2018; 4(3): 1068.