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SM Journal of Neurological Disorders and Stroke

Proliferating Astrocytes in Developing Brain and Reactive Astrocytes in Neurological Disorders

[ ISSN : 3067-9982 ]

Abstract
Details

Received: 25-Apr-2016

Accepted: 26-Apr-2016

Published: 28-Apr-2016

Editorial | Volume 2 - Issue 1 | Article DOI :

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Min Zhou

Department of Neuroscience, The Ohio State University Wexner Medical Center, United states.

Corresponding Author:

Min Zhou, Department of Neuroscience, The Ohio State University Wexner Medical Center, United states.

Keywords

Postnatal Brain; Astrocytes; CNS

Abstract

The neonatal astrocytes used to be considered a population of stage specific, proliferating immature astrocytes. Over the course of brain maturation, the newly generated astrocytesundergo extensive changes in gene expression, form spatially exclusive domains, connect through gap junctions into a syncytial network, and interact with and envelop blood vessels as part of the blood brain barrier [1-8]. Over the past two decades, increasing evidence shows that the very same “immature” astrocytes are the sculptors of synaptogenesisand facilitators of myelination in the CNS [8-10].

Citation

Zhou M. Proliferating Astrocytes in Developing Brain and Reactive OPEN Astrocytes in Neurological Disorders. SM J Neurol Disord Stroke. 2016; 2(1): 1006.