Keywords
s IGF; Neo-neuronal myelination; Serum; Breast-feeding
Abstract
Recent findings elucidate the significance of lower levels of serum IGF (insulin-like growth factor-1) in premature neonates compared to full-term gestations. IGF is a key promoter of neo-neuronal myelination and connectivity in the developing brain. The lower concentration of serum IGF in preemies than in term infants could account for a higher incidence of neuropathologic outcomes such as autism in the former than the latter. A practical, economical approach for reducing this potential risk could be breast-feeding exclusively for the first year of life in both cases since human milk has a higher concentration of IGF than bovine milk or formula
Citation
Steinman G. Reduction of Neonatal Neuropathology. SM J Neurol Disord Stroke. 2017; 3(2): 1015s5.