Keywords
Eccrine; Skin; Adnexal; Recurrence; Metastasis
Abstract
Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium that represents 0.005-0.01% of all cutaneous tumors. EPC can present as a primary tumor or, more commonly, as a malignant transformation of an eccrine poroma (EP). Eccrine and apocrine neoplasms present a bewildering array of morphologies, which often defy precise classification. This case describes a 62-year-old female with a soft tissue ulcerated mass at the front aspect of right thigh that reoccurred two years after a wide local excision was performed. EPC represents a problematic diagnosis as it is a locally aggressive neoplasm, with high recurrence rates, metastases to lymph nodes and to distant solid organs. While initial surgical treatment is curative for most of the cases, no standard treatment protocols exist for metastatic EPC. Clinicians, therefore, need to be aware of this rare entity, as porocarcinomas often show a marked morphologic variability, which has led to misdiagnosis and delayed treatment with disastrous consequences.
Citation
Barber C, Wichelt E, Braden L, Kaizer R, Emogene L, et al. (2020) Eccrine Porocarcinoma, a Rare Skin Adnexal Tumor. Report of a Case and Review of the Literature. SM Dermatol J 7: 5.