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SM Virology

Risk of Hantavirus Introduction and Establishment in Nepal

[ ISSN : 3067-9974 ]

Abstract Citation Letter to the Editor References
Details

Received: 30-Mar-2017

Accepted: 31-Mar-2017

Published: 03-Apr-2017

Yogendra Shah1,2,3, Basu Dev Pandey2,4, Kishor Pandey2 , Dhan Kumar Pant3 , Jeewan Thapa1 , Lila Nath Bhandari5 , Sarad Paudel6 , Rabin Kadariya7 , Krishna Prasad Panta8 and Sher Bahadur Pun5*

1Divison of Bio resources, Hokkaido University Research Center for Zoonosis Control, Japan

2Everest International Clinic and Research Center, Nepal

3National Zoo noses and Food Hygiene Research Center, Tahachal, Nepal

4Leprosy Control Division, Department of Health Services, Ministry of Health, Nepal

5Clinical Research Unit, Sukraraj Tropical and Infectious Disease Hospital, Nepal

6Department of Cell Physiology, Graduate School of Medicine, Hokkaido University, Japan

7Laboratory of Wildlife Biology and Medicine, Graduate School of Veterinary Medicine, Hokkaido University,Japan

8Faculty of Science and Technology, Far western University, Nepal

Corresponding Author:

Sher Bahadur Pun, Clinical research Unit, Sukraraj Tropical and Infectious Diseases Hospital, Teku, Kathmandu,Nepal;

Abstract

Hanta Virus (HV) is one of the major emerging and remerging zoonotic public health problems globally. These viruses are also known as rodent-borne viruses (zoonotic diseases) of the family Bunyaviridae that have been identified as etiological agents of two human diseases, Hemorrhagic Fever with Renal Syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS) [1,2]. Hanta virus first outbreak was reported during the Korean War from 1950 to 1953, where more than 3000 united nation troops fell ill with Korean hemorrhagic fever caused by HFRS. HV outbreak was also occurred in the four corners region of the United States in 1993 and which is now referred as Hanta Virus Pulmonary Syndrome (HPS) [1,3,4]. Now a days, owing to improved diagnostic facilities and surveillance efforts the presences of Hanta viruses are increasingly being reported in humans and rodents from Far East Russia, China, and South Korea [5-9].

Citation

Shah Y, Pandey BD, Pandey K, Pant DK, Thapa J, Bhandari LN, et al. Risk of Hantavirus Introduction and Establishment in Nepal. SM Virol. 2017; 2(1): 1012

Letter to the Editor

Hanta Virus (HV) is one of the major emerging and remerging zoonotic public health problems globally. These viruses are also known as rodent-borne viruses (zoonotic diseases) of the family Bunyaviridae that have been identified as etiological agents of two human diseases, Hemorrhagic Fever with Renal Syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS) [1,2]. Hanta virus first outbreak was reported during the Korean War from 1950 to 1953, where more than 3000 united nation troops fell ill with Korean hemorrhagic fever caused by HFRS. HV outbreak was also occurred in the four corners region of the United States in 1993 and which is now referred as Hanta Virus Pulmonary Syndrome (HPS) [1,3,4]. Now a days, owing to improved diagnostic facilities and surveillance efforts the presences of Hanta viruses are increasingly being reported in humans and rodents from Far East Russia, China, and South Korea [5-9].

According to Nepal government data, Ministry of labour and employment, more than 5000 Nepalese migrant workers are employed in South Korea annually through the Employment Permit System (EPS) [10]. Till to date, no laboratory confirmed cases of HV have been reported from Nepalese migrant workers who return back to Nepal, however, deaths attributed to pneumonia due to unspecified organism remains highest in Nepal [11]. HPS and pneumonia share similar clinical presentations, while physicians do not consider HV infection in their differential diagnosis in Nepal.

Thus, to prevent possible introduction and establishment of hanta virus infection in Nepal, Nepal government should provide specific training program for laboratory personnel and require effective surveillance for rapid and early detection of hanta virus infection in Nepal.

References

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7. Klempa B, Tkachenko EA, Dzagurova TK, Yunicheva YV, Morozov VG, Okulova NM. Hemorrhagic fever with renal syndrome caused by 2 lineages of Dobrava hantavirus, Russia. Emerg Infect Dis. 2008; 14: 617-625.

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9. Krüger D H, Ulrich R, Lundkvist A. Hantavirus infections and their prevention. Microbes Infect. 2001; 3: 1129 1144.

10. Ministry of labour and employment, employment permit system section, Kathmandu, Nepal.

11. Government of Nepal, Ministry of Health, Department of Health Services. Annual health report 2015-2016.