Medical tamsulosin therapy in children has shown encouraging results in facilitating spontaneous clearance of lower ureteral calculi.

In this paper we report 5 paediatric cases of tamsulosin use in clearance of distal ureteral stones. All patients showed typical symptoms of sudden onset of abdominal/ flank acute pain and were diagnosed by imaging findings.

We report this case series to emphasize the importance of tamsulosin as initial option to treat urolithiasis in children at the emergency room

Down’s syndrome is a chromosomal disorder caused by an error in cell division which results an additional third chromosome 21 or trisomy 21. The incidence of Down syndrome is 1 in 600 to 1000 live births. This condition leads to developmental delay, both mentally and physically. It is named by a British physician John Lang Down. There is no treatment but can be managed by early childhood intervention and proper care can improve quality of life

Acute pancreatitis is defined as an acute inflammation of the pancreas that may also involve peripancreatic tissues and/or remote organ systems. Although the common causes of acute pancreatitis are gall stones and alcohol consumption, drug induced cases are also reported frequently. Whereas steroids induced pancreatitis cases were less and rarely reported so the true incidence is unknown, quality of the evidence is limited since the availability of studies is very less. Prednisolone is a commonly used intermediate acting corticosteroid. It is a challenge to physicians to diagnose the drug induced pancreatitis than other causes. Here in this case report we describe a 22-year-old male patient who had received prednisolone tablet for Nephrotic syndrome. According to Naranjo’s ADR probability scale, the reaction was probable cause for acute pancreatitis.

SCC is an uncommon and aggressive breast neoplasm. There are limited data in literature about its epidemiology and studies focusing on outcomes, so they are still unclear. It has significantly worse prognosis than other non squamous cell tumors of the breast. Strict histologic criteria should be used to determine diagnosis. Because of its rarity, it is still unclear which the most appropriate therapeutic regimen to use is. The role of different new chemotherapy regimens needs to be explored and biologic studies are needed to determine the tumour chemoresistance mechanisms and the potential use of other treatment targets that improve patients survival. Clinicians should be aware of the aggressive nature of the tumour when counseling patients

The severity of malaria depends on factors some of which are well known. They allow a better understanding of the conditions of the risk of severe, and adopt the terms of surveillance and prevention. We report a case of Plasmodium falciparum polycythemia protected against deadly cerebral malaria.