Background: The association between Hodgkin lymphoma and IgA nephropathy is rarely reported.

Case presentation: A 20-year-old Saudi female patient presented with picture of immunoglobulin A nephropathy and prurigo nodularis. The patient was treated with oral steroid for 6 months; however, by the end of the course, she developed fever, night sweet, and weight loss. Work up was positive for Hodgkin lymphoma involving mediastinal lymph nodes, which was treated with chemotherapy and radiation. Both prurigo nodularis and IgA nephropathy are in complete remission 4 years after cure of lymphoma.

Conclusion: The temporality in presentation and sustained renal remission following lymphoma treatment, may suggest a causal association. Therefore, considering underlying lymphoma in patients with IgA nephropathy may be suggested.

Keywords: Immunoglobulin A (IgA) nephropathy; Proteinuria; Prurigonodularis; Hodgkin lymphoma; Lymphoma

Core tip: The association of IgA nephropathy with Hodgkin’s lymphoma is very rare. In this case report, the temporality and persistent complete remission of proteinuria after lymphoma cure suggest a causal link.

Atrioventricular Block (AVB) during pregnancy is a rare disease that a disorder of the cardiac conduction system. AVB could be asymptomatic. It istypical of permanent bradycardia and may cause to weakness, dizziness, dyspnea, syncope or heartfailure. Patient with AVB must evaluate with somenon-invasive techniques such as transthoracic echocardiography, treadmill test, and holter monitorization because of determining the prognosis of the disease. The reareno established guidelines for clinical management of the AVB in pregnancy. Although it is asymptomatic if a patient with AVB has complaints such as recurrent syncope and heartfailure, permanent pacemaker recommend. In ourcase, we presented pregnant women with AVB that was not need a permanent pacemaker.

Objective: To describe a case of a patient with bladder schistosomiasis, assessing the relationship between macroscopic and microscopic bladder schistosomiasis lesions.

Methods: We report the case of a 26 years old male patient with diagnosis of bladder schistosomiasis. We describe the clinical features, diagnosis, treatment and follow-up. We study and take separately biopsies of the macroscopic bladder lesions to further histopathological analysis.

Main results: The patient suffered hematuria and the diagnosis was confirmed by microbiological and histopathological studies. A course ofPraziquantel was prescribed. After the diagnosis of schistosomiasis and transurethral resection of bladder, the patient is still undergoing controls because of the associated risks of the disease. The histological analysis showed modifications from normality but neither differences between the different lesions nor cancer specific pre-malignant lesions.

Conclusions: The patients who have suffered severe urinary schistosomiasis must complete long-term follow-up. The endoscopic and histological correlation doesn’t show different patterns of aggressiveness.

Despite the benign features that constitute the majority of pleomorphic adenomas, there are rare instances where malignant transformations have been noted to occur. The most common of these transformations is carcinoma ex-pleomorphic adenomas. This subset can be further classified by unique histological variations that represent their malignant component. We present an unusual case of a rapidly enlarging parotid mass discovered to be a sarcomatoid carcinoma ex pleomorphic adenoma. This case will address the different categories of malignant mixed tumors, discuss the prevalence and clinical relevance of their histological sub classifications, and highlight different treatment modalities.

Intravenous Regional Anaesthesia (IVRA) is most commonly used for distal upper extremity operations. A patient was scheduled for the removal of a foreign body after trauma to her left hand under IVRA. A double-cuffed tourniquet applied and a dose of 15 ml 2% prilocaine was injected IV with 15ml with 0.9% NaCl via cannula. Within seconds of accidental cuff deflation, the patient developed nystagmus and aphasia and later developed seizure-like activity affecting her upperlimbs. The patient was treated with 60 mg propofol IV and ventilated with 100% oxygen. After 10 minutes she became alert and responsive to verbal commands and started speaking normally. Aphasia and difficulty in swallowing developed again after approximately 30 minutes and continued for two hours, after which symptom disappeared in less than five minutes. The serious risk of local anaesthetics systematic toxicity which may occur due to tourniquet problems or overdosage of the local anaesthetic.