In ancient medical handbooks, Hippocrates and Galen declared cancer as an incurable disease. Since Greek antiquity this two minds have shaped the current practice of medicine and their grim statement about cancer therapy remains a major challenge for our species in the 21 century. Our increasing understanding of cancer biology has led to the development of molecularly targeted anticancer drugs. The promising outcomes of targeted therapies and the incremental improvements in patients’ survival have given hope for a complete cancer remission. Unfortunately, targeted therapies are currently facing the presence of tumour resistance, often resulting from compensatory signalling pathways, or from the development of acquired resistance in cancer cells via clonal evolution under the selective pressures of treatment. Exploring the role of tumour heterogeneity in the development of drug resistance lead to a new perception of cancer as a complex, dynamic and adaptive ecosystem underpinned by genetic diversity and epigenetic plasticity. Despite this negative aspect, inherent Darwinian character of cancer cells alternatively paves the way towards novel opportunities for the development of revolutionary cancer therapies.

In the recent years, the frequency and the geographic distribution of jellyfish blooms have been increased in the Mediterranean north-west coastline of Morocco, since 2011 this area has been subjected to successive blooms and stranding of Pelagia noctiluca; our research was aimed to study the causes of jellyfish blooms and stranding in our coastline. We have evaluated three parameters that we are suspecting to be responsible of Jellyfish stranding on the northern coast of the Mediterranean Sea in Morocco. The evaluation of the relations between sea surface temperature, waves height and the wind direction causing the stranding of Jellyfish, demonstrated that the correlation scores was found to be statistically significant with r(33) =0.445, p < 0.01, for sea surface temperature (°C) and r(33) =0. 694, p