Intrahepatic Cholestasis of Pregnancy (ICP) is the most common pregnancy-related liver disease and is characterized by onset of pruritus and elevated serum transaminases and Bile Acids (BA) in the third trimester of pregnancy. Symptoms and abnormal liver tests resolve following delivery but frequently recur in subsequent pregnancies [1]. We represent one 37 years old female who had Intrahepatic Cholestasis of Pregnancy (ICP) in three pregnancies at intervals of 2 and 10 years.

Posterior cord neurostimulation therapy is used to treat several syndromes such as complex regional pain. Many patients treated in this way are young women of a reproductive age, who subsequently can become pregnant, although the effects of this therapy during pregnancy and on the development of the fetus are still unknown.

We present a clinical case of a 26 year-old patient who became pregnant after posterior cord neurostimulator implantation. The purpose is to review and synthesize the existing literature and recommendations about the use of neurostimulation during pregnancy and childbirth.