Background: In Canada, industrial wind operations are important parts of the country’s long-term energy strategy and Wind Turbines (WTs) are represented as environmentally friendly projects; however, suspected health-related effects of exposure to WT noise have attracted much public attention. Sleep disturbance and degraded Health-Related Quality of Life (HRQoL) have been among the most common complaints reported by residents living close to wind farms.

Objective: The objective of this study was to evaluate the association between changes in sleep quality and HRQoL among residents living close to wind farms.

Methods: Pre- and post-natural experiments were conducted with two data collection periods, before and after WTs became operational; sleep quality was measured by using the Pittsburgh Sleep Quality Index (PSQI), and HRQoL was measured using the 12-item Short Form (SF-12) Health Survey of 50 participants.

Results: Changes in the SF-12 mental component summary (ΔMCS) were correlated inversely with the changes in PSQI score (ΔPSQI, Spearman’s correlation r_S= -0.595). The median values for ΔMCS were significantly associated with ΔPSQI (p=0.039) after controlling for age, sex, distance and attitude to WTs, in a quantile regression analysis.

Conclusion: Changes in sleep quality reported by residents living nearby WTs were a significant independent predictor of the degraded mental health domain of HRQoL.

Acute psychiatric illness is associated with alterations of serum thyroid hormone levels including normal or high T3 levels and elevated T4 levels with normal or high TSH that have no clinical signs or symptoms and resolve within 2 weeks. This phenomenon is called euthyroid hyperthyroxinemia. We present a case of primary hyperparathyroidism contributing to a patient’s depression with psychosis that developed euthyroid hyperthyroxinemia. We also review the literature to present current thoughts about pathophysiology and treatment.

This study investigated potential correlation between the inflammatory marker, Calprotectin, and a S.O.S questionnaire from forty-nine Autistic children. Symptom and behavioral questionnaires were completed contemporaneously with stool sample collection. Mixed Model data analysis showed strong correlation between some questionnaire parameters and Calprotectin. ‘Need for a fixed routine’ was highly significantly correlated with Calprotectin (????<0.00009) with Multivariate Coefficient of 3.227, whilst paradoxically ‘constipation’ indicated significant change (????<0.02) with negative Multivariate Coefficient (-1.584). The negative ‘constipation’ appears to associate with the positive ‘need for a fixed routine’ indicating possibility of reciprocal, independent prediction of gastrointestinal inflammation. Results suggest that ‘need for a fixed routine’ and ‘constipation’ be included in a screening questionnaire as independent predictors of bowel dysfunction in these children.

Background: Improved real world functioning is the ultimate goal of cognitive rehabilitation (which was developed for an acquired brain injury population), however, cognitive remediation for psychiatric populations focuses primarily on cognitive interventions (e.g., computerized cognitive training) and utilizes cognitive test results as outcomes. A broader range of neuropsychological interventions and outcome measures, incorporating real-world measures of functioning, is recommended for cognitive remediation program evaluation.

Objective: To determine the feasibility and explore the effectiveness of a holistic cognitive remediation program administered by clinical neuropsychologists for a community-based mixed psychiatric treatment seeking sample.

Method: Twenty-five adults of mixed psychiatric aetiology were referred for a 10-week intervention (including four hours of weekly individual and group-based sessions). A broad array of outcomes was assessed post-intervention. Functional status, self-reported cognitive symptoms and quality of life was assessed at 11.3 months follow-up.

Results: Eighteen of the referred participants (72%) completed the intervention. Completers showed: a high rate of functional cognitive goal attainment; increased employment rates; improved symptoms of psychological distress and quality of life; reduced self-report of cognitive difficulties; and improved auditory attention span and verbal memory. Self-report of reduced cognitive difficulties and improved quality of life was maintained approximately one year later. The majority of participants reported very high levels of satisfaction with the program.

Conclusions: This intervention was acceptable to participants and associated with high satisfaction rates and gains in cognitive, psychological and functional outcomes. Findings suggest there are multiple benefits to adopting an intervention program that is holistic, individualized to the goals of the patient and facilitated by trained neuropsychologists.

One-third of people living with dementia also experience depression. Treating symptoms of depression may be a protective factor and reduce cognitive decline in dementia. People suffering from depression experience sad mood, reduced energy, poor concentration, loss of interest, diminished activity and they are at risk for death by suicide. Screening instruments include the Cornell Scale for Depression in Dementia (CSDD) and the Geriatric Depression Scale (GDS). Typical treatments include antidepressant medications, which may have limited efficacy; and Electroconvulsive Therapy (ECT), which may heighten memory loss. Psychotherapeutic approaches, including cognitive–behavioral therapy, interpersonal therapy and supportive counseling can be helpful. Lifestyle modifications addressing healthy diet, exercise and the inclusion of enjoyable activities can promote improved quality of life. Providing needed education and support to caregivers, who often experience depression, anxiety and sleep disorders themselves is critical. This paper provides health professionals with an overview of approaches for recognizing and responding to co-occurring dementia and depression.