An asymptomatic 36-year-old woman presented to our hospital for a routine ophthalmic examination. Slit lamp biomicroscopy revealed in her right eye tiny pigmented opacities on the anterior lens capsule.

Purpose: To compare the change in asphericity and other Higher Order Aberration (HOA) in Custom-Q vs. Wavefront Optimized (WFO) LASIK ablation profile patients in an Asian population.

Setting: Prospective matched-cohort study in refractive center.

Method: Thirty-four eyes of 17 patients with myopia seeking laser correction at Nobel Clinic in Taipei, Taiwan were enrolled in a prospective cohort study. Utilizing the latest WaveLight®EX500 Excimer Laser (Alcon, Inc., Switzerland), each patient received both Custom Q (CQ) and WFO LASIK ablation treatments (CQ on OD and WFO on OS). Each patient was measured thrice, as follows: (1) Before the Lasik procedure, (2) 1 week after the procedure, and (3) 1 month after the procedure.

Results: The custom-Q ablation group comprised a mean SE of -5.32 diopter (D), and the WFO ablation group comprised a mean SE of -5.41 diopter (D). Their frequencies with which Custom-Q and WFO achieved postoperative Uncorrected Distance Visual Acuity (UCDVA) were not statistically different from each other (P>0.05). No statistically significant differences were found in contrast sensitivity, astigmatism, coma, and trefoil. However, the change of spherical aberration was higher in the WFO ablation profile. Patient questionnaire shows a mild preference for Custom-Q over WFO.

Conclusion: Custom-Q and WFO LASIK provided similar results in myopic refractive correction and achieved post op UCDVA and contrast sensitivity. However, Custom-Q produced less changes in asphericity and HOA changes; Asian patients showed marginal preference for Custom-Q in terms of optic quality.

In Germany about 30 thousand patients are affected by one of the over 100 forms of inherited degenerative diseases of the retina, worldwide about 2 million.

Background/Purpose: To evaluate the effectiveness of primary neodymium-doped yttrium aluminum garnet (Nd:YAG) laser posterior capsulotomy in pediatric cataract surgeries.

Methods: Retrospective analyses of 19 eyes of 11 patients with developmental cataract who had undergone cataract surgery between 2012 to 2016 were included in the study. All the cases that had undergone phacoemulsification with foldable acrylic Intra Ocular Lens (IOL) in which the posterior capsule was left intact, and followed by Nd:YAG capsulotomy after one to two weeks’ of surgery were included. Traumatic cataracts and those which needed anterior vitrectomy due to dehiscence of posterior capsule were excluded from the study.

Results: The mean age of the study population was 7.42 ± 3.39 years withaminimum age of 3 years andamaximum of 14 years. The maximum follow-up period was found to be 33 months. The mean preoperative visual acuity in the study group was 0.87 log MAR units anda statistically significant improvement was noted post operatively. All 19 eyes had a clear visual axis at thelast follow up. No eye developed visual axis opacification or required any further intervention.

Conclusion: This study proposes that leaving the vitreous undisturbed and performing YAG capsulotomy after two weeks is moreeffective than a primary posterior capsulorhexis with anterior vitrectomy especially in children older than 3 years. It is a safe and easier method even at the hands of inexperienced surgeons who may have to take up a developmental cataract in under developed and less accessible parts of the world.