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JSM Clinical Cytology and Pathology

Diagnosis of Lymphadenopathic Kaposi Sarcoma by Fine Needle Aspiration in a non-HIV patient. Case report with uncommon presentation and brief review of the literature

[ ISSN : 2689-1549 ]

Abstract
Details

Received: 14-Jul-2020

Accepted: 27-Jul-2020

Published: 29-Jul-2020

Case Report | Volume 2 - Issue 2 | Article DOI :

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Matthew White*, Alexandria Kim, Nicole DiTommaso, David Kim, Kaitlyn Takach, Ibrahim El-Mais, Barish Eren, and Mohamed Aziz

Department of pathology, American University of the Caribbean School of Medicine, USA (#1 University Drive at Jordan Road, Cupecoy, Sint Maarten)

Corresponding Author:

Matthew White, American University of the Caribbean School of Medicine, USA (#1 University Drive at Jordan Road, Cupecoy, Sint Maarten), Tel: (403)272-8516; E-mail: matthewwhite@ students.aucmed.edu

Keywords

Sarcoma; Immunohistochemistry; Lymphadenopathy; Aspiration; Castleman

Abstract

This report presents the diagnosis of Kaposi sarcoma by the minimally invasive procedure of fine needle aspiration. The patient, a 65-year-old HIV negative Mediterranean man with a history of colon cancer, presented with right inguinal lymphadenopathy. Biopsy of the lymph node showed histological morphology consistent with Kaposi sarcoma confirmed by HHV-8 positive immuno stain. We review the role of HHV-8 in the pathogenesis of Kaposi sarcoma. We also discuss how it presents differently than Multicentric Castleman disease of the lymph node, caused by the same virus. How the latent and lytic pathways of the virus can influence the progression of the Kaposi sarcoma and Multicentric Castleman disease, respectively. Also, we review various treatment modalities for Kaposi sarcoma.

Citation

White M, Kim A, DiTommaso N, Kim D, Takach K, et al. (2020) Diagnosis of Lymphadenopathic Kaposi Sarcoma by Fine Needle Aspira tion in a non-HIV patient. Case report with uncommon presentation and brief review of the literature. JSM Clin Cytol Pathol 2: 4.