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JSM Clinical Cytology and Pathology

Lobular Carcinoma of the Breast Presenting as a Metastatic Melanoma to the Axilla: Report of a Case and Review of the Literature

[ ISSN : 2689-1549 ]

Abstract
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Received: 13-May-2020

Accepted: 28-May-2020

Published: 01-Jun-2020

Case Report | Volume 2 - Issue 2 | Article DOI :

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Joseph Varney¹, Shanli Parnia¹, Amanda Rivera¹, Sherif AbdelAziz², Makenzie Gairrett¹, Hannah Pulido¹, Mohamed Aziz¹*

¹ Department of Pathology, American University of the Caribbean (AUC) School of Medicine, USA
² Walter Reed National Military Medical Center, Bethesda, MD, USA

Corresponding Author:

Joseph Varney, American University of the Caribbean, USA, Tel: 561-460-3270; E-mail: themedicalmuscle@gmail. com

Keywords

Immunocytochemistry, Invasive. Metastatic. Lobular. Carcinoma, Melanoma

Abstract

Metastatic melanoma may simulate a broad spectrum of primary malignant tumors. Significant similarity in cytomorphologic features can exist in both melanoma and lobular carcinoma of the breast. This can cause significant diagnostic difficulty, especially when there is inadequate patient history and/or limited biopsy material. The extraordinary phenotypic plasticity of metastatic melanoma adds to the diagnostic challenge of these tumors. Awareness of this pattern variance is essential to avoid diagnostic errors and inappropriate treatment. Here we present a case of metastatic lobular carcinoma, which was initially diagnosed as metastatic melanoma. Awareness of the similar cytomorphologic features of both melanoma and lobular carcinoma as well as the use of immunohistochemistry studies aided in providing the final diagnosis of this case and avoiding a diagnostic error.

Citation

Varney J, Parnia S, Rivera A, AbdelAziz S, Gairrett M, et al. (2020) Lobular Carcinoma of the Breast Presenting as a Metastatic Mela noma to the Axilla: Report of a Case and Review of the Literature. JSM Clin Cytol Pathol 5: 4.