Buabeng KO1*, Agyapong T2, Owusu IK3, Koffour GA2 and Ansah CA2
1Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
2Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, KNUST, Kumasi, Ghana
3The Cardiac Clinic, Komfo Anokye Teaching Hospital/Department of Medicine, School of Medical Sciences, College of Health Sciences, KNUST, Kumasi, Ghana
Corresponding Author:
Dr. Kwame Ohene Buabeng. Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana. Email: koheneb@hotmail.com
Abstract
Many chronic disorders are often managed with diverse pharmacological agents or fixed dose combination due to the complementary mechanism of the drugs which have additive or synergistic effects. In the face of different co-morbidities, combination therapy with two or more agents often adequately control the multifactorial risk factors associated with such diseases. Multidrug therapy also permits lower doses of each agent to be utilized and attenuates the side effects associated with higher doses in monotherapy
Citation
Buabeng KO, Agyepong T, Owusu IK, Koffour GA and Ansah CA. Multidrug Therapy and Risk of Adverse Drug Reactions in Africa: The Need to Step Up Pharmacovigillance to Improve Patient Health and Safety. SM J Pharmac Ther. 2016; 2(2): 1011s3.
