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SM Journal of Pharmacology and Therapeutics

Paclitaxel Delivery Systems; From A Stubborn Undruggable To an Efficient Chemotherapeutic In Clinic

[ ISSN : 2574-2396 ]

Abstract
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Received: 09-Mar-2016

Accepted: 14-Mar-2016

Published: 18-Mar-2016

Editorial | Volume 2 - Issue 1 | Article DOI :

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Farid A Dorkoosh¹,², Pouya Dehghankelishadi¹,² and Shabnam Samimi¹,²*

¹ Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Iran
² Medical Biomaterials Research Center, Tehran University of Medical Sciences, Iran

Corresponding Author:

Farid A. Dorkoosh, Tehran University of Medical Sciences, Iran, Tel/Fax: +098 21 88009440; Email: Dorkoosh@tums.ac.ir

Abstract

Excessive proliferation of cancer cells could be inhibited by disruption of microtubule network. Paclitaxel (PTX), a well-known chemotherapeutics, stabilizes microtubule networks and consequently interferes cell division. As other chemotherapeutics, pharmacodynamics of PTX seems to be promising

Citation

Dorkoosh FA, Dehghankelishadi P and Samimi S. Paclitaxel Delivery Systems; From A Stubborn Undruggable To an Efficient Chemotherapeutic In Clinic. SM J Pharmac Ther. 2016; 2(1): 1011s.