Keywords
Neurodegenerative Diseases; y brain impairments
Abstract
There is a clear sex bias in the incidence, prevalence and outcome of many neurodegenerative disorders. The high incidence of these diseases in an increasingly aging population has raised interest in understanding the relevance of sex in the progression of these diseases and their treatment. Important sex differences have been reported in autoimmune, neurodegenerative and mood related disorders.
In this review, we take an insight in the differential evolution of some neurodegenerative diseases depending on the sex, highlighting the importance of gonadal hormones in this process, and the implications of a proper understanding of the mechanism underlying these differences for the therapeutic strategies for the prevention and treatment of these diseases.
Citation
Yanguas-Casás N. Sex Differences in Neurodegenerative Diseases. OPEN SM J Neurol Disord Stroke. 2017; 3(1): 1014.