Abstract
Organ transplantation has become an essential treatment for saving and prolonging lives in a wide range of clinical disorders. It is a complex procedure and often convoluted by distinct issues related to clinical outcome and number of donors [1]. Recent attempts to overcome these problems have been demonstrated in the field of regenerative medicine [2]. Regenerative medicine is a branch of medicine involved in the development of methods for the regeneration and repair of tissues and organs damaged by age, diseases or congenital defects. It encompasses numerous strategies including the use of biomaterials, stem cells and bio-cues or any combinations thereof, to promote tissue healing [3]. In this context, Human Bone Marrow Stromal Stem Cells (MSCs) have proved to be an effective source for transplantation due to their capacity to self-renew and differentiate both in in vitro and in vivo while restraining concerns regarding immune response and ethical and legal administration [4].
Citation
Perugini V. A Cross-Platform Challenge behind the Role of Human Mesenchymal Stromal Cells in Organ Transplantation. SM J Surg. 2018; 4(1): 1020s.