Onychomadesis is a periodic idiopathic shedding of the nails beginning at the proximal end, possibly caused by the temporary arrest of the function of the nail matrix. Infections, stress in utero has been reported as the initiating factor in each of this entities. We report a one year-old infant, affected by onychomadesis, occurred after cesarean childbirth following Stresses in utero by severe maternal pyelonephritis.

Pili annulati is a disorder that produces a spangled appearance to the hair, caused by alternating light and dark banding of hair shafts. Complications of pili annulati are limited; the most noteworthy complication is increased breakage.We report a case of Pili annulati associated With Hair Fragility, based on clinical examination and dermoscopic examination findings.

Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium that represents 0.005-0.01% of all cutaneous tumors. EPC can present as a primary tumor or, more commonly, as a malignant transformation of an eccrine poroma (EP). Eccrine and apocrine neoplasms present a bewildering array of morphologies, which often defy precise classification. This case describes a 62-year-old female with a soft tissue ulcerated mass at the front aspect of right thigh that reoccurred two years after a wide local excision was performed. EPC represents a problematic diagnosis as it is a locally aggressive neoplasm, with high recurrence rates, metastases to lymph nodes and to distant solid organs. While initial surgical treatment is curative for most of the cases, no standard treatment protocols exist for metastatic EPC. Clinicians, therefore, need to be aware of this rare entity, as porocarcinomas often show a marked morphologic variability, which has led to misdiagnosis and delayed treatment with disastrous consequences.

Kaposiform hemangioendothelioma (KHE) is a rare, locally invasive vascular tumor with intermediate malignancy situated somewhere between the spectrum of hemangioma and angiosarcoma. It is known to be locally aggressive, infiltrating the surrounding tissue, but with no firm evidence of metastatic potential. KHE can be diagnostically challenging due to the known histomorphologic overlap among different endothelial lesions with varying malignant potential. Although the infiltrating pattern of KHE is well documented, it rarely infiltrates the adjacent bone. Treatment approach for these tumors is not consistent, largely because cases are rare and managed by various specialists in different fields. We report a case of paraspinal KHE, an unusual location for this tumor, and discuss the benefit for rehabilitation for all patients with KHE, especially patients with musculoskeletal complications caused by the tumor.

A 63 year-old non-smoker woman with a 15 years history of rheumatoid arthritis characterized by erosive poliarthrtitis, rheumatoid factor elevated titers, and positive testing for anti-CCP antibodies. The treatment included methotrexate, prednisolone and hydroxicloroquine. Despite of treatment, developed isquemic ulcer at left hand dorsum and nailfod infarction and digital ischemia of the left fingers.

Rheumatoid vasculitis is an inflammatory process that primarily affects small to medium-sized vessels. It’s highly heterogeneous clinically, with wide-spread organ involvement. The incidence has declined in the past several decades, but cutaneous remains the most common presentation. It tipically occurs in patients with longstanding erosive deforming Rheumatoid Arthritis, and it’s manifestation is heterogeneous, dependeing the size of the blood vessel. The skin can presents purpura, nailfold infarcts, digital gangrene and cutaneous ulcers.