Objective: This study aims to investigate the effect of ibandronate, which is a biphosphonate and acts by inhibiting osteoclasts in osteoporosis treatment, on fracture healing in rat tibia model.

Material and Method: 60 Wistar-Albino type male rats were divided into two groups as study (ibandronate) and control. Under general anesthesia standard closed fractures were created on right tibias of all rats using blunt ended needle holder by three point principle and then closed reduction and fixing with intramedullary nail (0.5 mm) were provided. The day of fractures were created, one oral dose of 250 μg ibandronate (Bonviva® tablet 150 mg, Roche, Istanbul, Turkey ) was given to each group A, B, C and D. 1 month after 250 μg oral dose administration to groups E and F the day the fractures were created, the second dose of 250 μg ibandronate was administered. The rats were killed at 2nd week in groups A and B, at 4th week in groups C and D, and at 6th week in groups E and F. Oral administrations were performed by the same person with 15 gauge plastic feeding through nasogastric gavage. Fracture healing was evaluated as biomechanically, radiologically and histologically.

Results: No positive or negative radiological, biochemical and histological effect of ibandronate was detected, starting from the first day and reaching to 6 weeks, in healing process of closed tibia fractures created and fixed with IM nails in rats.

In the year 1879 [1], Paul Segond mentioned about the Anterolateral Ligament (ALL) for the f irst time in orthopedic literature.

Lateral Epicondylitis, or more commonly called “tennis elbow,” is a musculoskeletal condition characterized by pain upon extension and contraction of the fingers, wrist, and elbow. Such elbow pain can oftentimes be debilitating, as patients find themselves unable to work, enjoy their hobbies, or perform simple household tasks

Objectives: As regards osteoarthritis (OA), conventional treatment has still not given total satisfaction to our patients. This may explain their use of Complementary and Alternative Medicine (CAM) which could easily interfere with the physician prescription. The aim of the present study was to determinate the prevalence of CAM use by knee OA patients and to assess its predictive factors.

Methods: A cross-sectional study was set at the university hospital. Patients with knee OA according to the American college of rheumatology were included. Information was collected about Knee OA patients, the different types of CAM used, the reasons for using CAM, and CAM’s effectiveness on pain and function. The doctor-patient relationship was also analyzed. We performed a statistical analysis with a logistic regression to determine predictive factors of CAM use.

Results: Of the 105 patients included in this study, 64.8 % used CAM at least once in their lives, 77.5% said they started CAM as soon as their OA had been diagnosed. Fifty eight percent of patients reported using CAM to relieve pain, while 18.4% were using it to cure their OA. Regarding the types of CAM, 72% of patients used massage with application of essential oils, 51.5% used balneotherapy, 22% used phytotherapy, 17.6% did cupping, 13.2% went to sand baths and 10.3% have used acupuncture. Olive and argon oil were the most used as topic agents. Eighty eight percent of patients admitted that their doctor was not aware about their use of CAM, because he had never asked about it in the majority of cases. After univariate analysis, there were no predictive factors for the use of CAM.

Conclusion: The use of CAM is frequent and various in our study. Health care providers should discuss these therapies with all OA patients, in order to assess their effectiveness, and to prevent their adverse effects.

The World Health Organization (WHO) defines osteoporosis as a disease characterized by low bone mass and deterioration of the micro architecture of bone tissue, which causes an increased brittleness of the same, with a consequent increase in fracture risk. Osteoporosis affects more than 200 million individuals in the world, potentially 5 million people in Italy, of which 80% post-menopausal women.

In the daily practice of Orthopedics and Traumatology departments is very frequent hospitalization for fracture of the femoral neck in elderly patients. In our study we observed 162 patients hospitalized with hip fracture diagnosis at two Italian hospitals. In most cases there were fragility fractures with previous diagnosis of osteoporosis, but patients had never received an anti osteoporotic therapy. The prescription of a medical therapy in patients with osteoporosis is an essential prevention of secondary fractures.