Aim of the Study: To find association between clinical features of systemic sclerosis and esophageal dysmotility disorder based on high resolution manometry (HRM) findings according to the 3rd version of Chicago classification.

Methods: In a cross-sectional study in Firozgar hospital we recruited 150 consecutive SSc patients. All patients fulfilled the 2013 ACR/EULAR classification for SSc criteria. We used water-perfused esophageal high resolution manometry (HRM) having 26-channel silicone-customized catheter.

Results: From all 150 SSc patients who were included in the study, forty-nine (46%) had dcSSc subset of disease with mean age (SD) 47.0 (12.1) years. According to the 3rd version of the Chicago classification, 135 (90%) patients had ineffective peristalsis [weak peristalsis in 24 (16.0%) and failed peristalsis in 111 (74.0%) of patients]. Hypotensive Esophagogastric junction pressure (hEGJP) presented in 47 (31.3%) patients. Two (1.3%) patients had achalasia in HRM. Age, gender, and duration of disease were not different in the above two groups of patients. In multivariate model FVC%, [OR (CI95%): 1.055(1.025-1.086), p<0.001] showed significant association with failed peristalsis.Comparison between average rank of FVC% in peristalsis status groups showed significant difference between average rank of FVC% in patients with failed peristalsis and weak peristalsis p=0.001, and average rank of FVC% in those with failed peristalsis and normal peristalsis p=0.020.

Conclusions: Our findings showed that esophageal dysmotility is a frequent finding in systemic sclerosis patients. The results demonstrated that FVC%, tendon friction rub kept significant concordance with failed peristalsis. Moreover, we noticed a concordance between HRM results and severity of FVC.

The subacromial impingement syndrome is a collective cause of shoulder pain it takes place due to the soft tissue reside in the subacromial space. This occurs by mechanical compression of the soft issues predominantly on the supraspinatus, long head of biceps tendon, subacromial bursae and superior portion of the articular capsule between the greater tuberosity and the under surface of the anteroinferior edge of the acromion. The root cause of this condition has been contested over the last couple of decades nowadays, many studies agree that this condition is multifactorial and management includes physiotherapy, injections, and surgery in some selected patients. This article aims to provide an overview of the clinical features and pathogenesis of subacromial impingement syndrome also discuss the widely accepted non-invasive physiotherapy interventions approach for recovering the subacromial impingement syndrome effectively and efficiently based on other studies.

Bone health is one of the important parts of healthy-life and longevity. In the current scenario, due to indiscriminate uses of pesticides in agriculture, there is a high abundance of toxins and contaminants in the environment and food chain. For this consequence, the present study has investigated the effect of the Biofield Energy Healing (The Trivedi Effect®) Based test formulation on bone health parameters using the human bone osteosarcoma cells - MG-63(ATCC® CRL-1427™). A proprietary formulation was designed that consisted of eight ingredients viz. zinc chloride, ferrous sulfate, sodium selenate, nanocurcumin, copper chloride, magnesium gluconate, vitamin C (ascorbic acid), and vitamin D3 (cholecalciferol). The test formulation was divided into two parts. One part was denoted as the untreated test formulation without any Biofield Energy Treatment, while the other part was defined as the Biofield Energy Treated sample, which received the Biofield Energy Healing Treatment by renowned Biofield Energy Healer, Mahendra Kumar Trivedi. The cell viability assay data of the test formulation showed more than 70% cell viability at the concentration ranges from 0.001 to 10 µg/mL, which indicated its safe and non-cytotoxic nature. Alkaline phosphatase enzyme (ALP) was significantly increased by 80.16%, 292.91%, 200.36%, 22.24%, and 690.35% in the Biofield Energy Treated test formulation group (G4) at 0.0008, 0.001, 0.0033, 0.052, and 10.41 µg/mL, respectively as compared to the untreated test formulation group (G3). As a result of that phosphorus absorption and deposition in bone cells can be increased which can help to make stronger bone. The data demonstrated that the Biofield Treatment has the strong potential for the treatment of patients with arthritis, osteoporosis, and other bone disorders. Thus, Consciousness Energy Healing can be useful as a bone cells growth promoter for different bone-related disorders like low bone density, osteogenesis imperfecta, osteoporosis, etc.

Introduction: The purpose of our study was to describe the epidemiological and therapeutic aspects of the proximal humerus fractures and to evaluate their functional results.

Materials and methods: This was a retrospective study about all patients operated for proximal humerus fracture at the South-Essonne Dourdan-Étampes Hospital Center between January 2016 and December 2017.

Results: 58 patients were operated. Women represented 65.5% with a female / male sex ratio of 1.9. The mean age was 67.3 years (17-95 years). Fracture following a fall in 86% and 60% concern the left side. according to the Neer classification, 65.5% were 2-parts fractures, 22.4% 3-parts fractures and 12% 4 or over 4 parts. In 19% were operated after orthopedic treatment failure. The telegraph nail represents 62% of used materials. 12% of the patients had benefited a total shoulder arthroplasty. At the last follow-up of 14 months (8-22 months) consolidation was achieved in 98% of osteosynthesis. The abduction average was 145 ° (45 ° - 180 °). Mean Constant score was 79 (64 - 95). 1 case of humeral head necrosis was noted and 5 cases of shoulder stiffness in abduction.

Discussion: We believe, as many authors, that many factors seem to influence functional evolution. The type of fracture influences the therapeutic choice and is the main predictor of functional outcome, failure, complications and re-intervention.

Conclusion: There is certainly no consensus in the management of the proximal humerus fracture, but many choices are currently available for surgeons. “Every age group is served”