Background: Alcohol Use Disorder (AUD) imposes a significant health burden on adolescents and young adults, contributing to both physical and mental health challenges. With varying impacts based on sociodemographic index (SDI) levels, this study provides a comprehensive assessment of the global and regional AUD burden, revealing critical patterns that influence public health strategies. To evaluate global trends in the burden of AUD among adolescents and young adults (aged 15-39 years) from 1990 to 2021. This study aims to assess prevalence, disability-adjusted life years (DALY), and mortality related to AUD, analyze disparities across sociodemographic categories, and identify factors associated with increased risk, focusing on the influence of socioeconomic and demographic factors on AUD. Methods: This study is a systematic analysis based on the 2021 Global Burden of Disease (GBD) dataset, encompassing individuals aged 15-39 years across 204 countries and territories over a 30-year period (1990-2021). A range of statistical approaches, including Age-Period-Cohort (APC) analysis, decomposition, frontier analysis, and predictive modeling, was employed to assess the trends in AUD burden by SDI, age, sex, and geographic location. The primary outcomes measured were age-standardized prevalence, DALY, and mortality rates for Alcohol Use Disorder among people aged 15-39 years. Results: Globally, age-standardized prevalence, DALY, and mortality rates for AUD among adolescents and young adults showed a declining trend from 1990 to 2021, with Average Annual Percent Changes (AAPC) of -0.97%, -1.03%, and -1.5%, respectively. Males consistently exhibited higher prevalence and DALY rates compared to females. High SDI regions demonstrated higher AUD burdens, while low and low-middle SDI countries showed slower reductions, with population growth being a significant factor in increasing AUD DALY in these regions. Conclusions: The findings underscore the need for targeted and context-sensitive interventions to reduce AUD burden, particularly in high-SDI regions where social and lifestyle factors increase risks, as well as in low-SDI regions facing limited resources. Tailoring prevention and intervention strategies to meet the unique socioeconomic and demographic needs of various populations could enhance the effectiveness of AUD management and public health outcomes globally.

Background: Traditional and Complementary Medicine (T&CM) becomes a truly global phenomenon. The primary health care recognizes its importance. Number of patients seeking T&CM treatments increased butmost of the health professionals is ignorant of the risks and benefits of T&CM because of lack of knowledge. Health professionals’ view on T&CM is very important for healthcare. The study was designed to assess the opinion of the health professionals in five selected hospitals in Malaysia on their perception of their practice of T&CM in Malaysia, usage and recommendation of T&CM, knowledge on T&CM, integrating T&CM into Conventional Medicine (CM), and opinion on future medical training in T&CM respectively.

Methods: An in-depth semi-structured face-to-face interview was carried out on ten health professionals from five selected hospitals in this qualitative study.

Results: All the participants used some types of T&CM personally and generally recommended T&CM for treatment in this study. Most of them agreed with the statement that T&CM is popular among the population and thought that people trusted in T&CM and were afraid of CM. All the medical staff believed that T&CM has therapeutic value. Almost all respondents agreed with the statement on an integration of T&CM with CM and most of them agreed for T&CM to be a part of future training for health professionals.

Conclusion: From the interview, it shows that all the participants have experienced in using some types of T&CM in their life for whatever reason they might have. However, a small number of participants have negative idea about T&CM but all the health professionals interviewed believed the therapeutic value of some types of T&CM.