
Does a High Protein Diet Induce Oxidative Damage?
T he purpose of the present letter is to determine the marginal level of high protein diet which modulates oxidative damage. The author hopes that the determination of the marginal level of high protein diet which modulates oxidative damage could contribute to the research for oxidative damage, apoptosis, obesity, cell proliferation, differentiation or cancer. Consumption of a high protein diet is of interest in terms of one of dietary interventions for weight loss. Camiletti-Moirón et al. [1] reported that a high protein diet induces oxidative damage to the brain in rats by means of lipid peroxidation or protein oxidation. In the paper, however, the diet contained 45% dietary protein for the high protein group compared to the basal protein group. If the diet contains more than the content (e.g., 60-80% dietary protein) in the experimental or clinical study, it is my opinion that an “excessive dietary protein” may be the suitable terminology for the level of dietary protein rather than a “high protein diet”.
Sung Jae Shin*