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Journal of Surgical Oncology & Clinical Research

Alveolar Soft Part Sarcoma: Case Report of a Rare Tumor and Review of Literature

[ ISSN : 3068-0727 ]

Abstract
Details

Received: 13-Feb-2022

Accepted: 31-Mar-2022

Published: 07-Apr-2022

Case Report | Volume 4 - Issue 1 | Article DOI :

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Glyn Hinnenkamp*, Amy Hackett, Brandon Grodman, Logan Primeaux , Ashley Green, Savannah Sadaiappen , Sylvester Bote, and Mohamed Aziz 

Department of Pathology- American University of the Caribbean, School of Medicine, USA

Corresponding Author:

Glyn Hinnenkamp, Department of Pathology, American University of the Caribbean School of Medicine, USA

Keywords

Alveolar soft part sarcoma; Soft tissue; Translocation; Immunotherapy

Abstract

Alveolar soft part sarcoma (ASPS) is a rare neoplasm occurring most frequently in the soft tissues of both children and adults, which has a tendency for an indolent course and late metastasis. It is characterized by an unbalanced translocation, der(17)t(X:17)(p11;p25), producing a fusion protein which has recently been shown to play a role in promoting cell proliferation and angiogenesis and may provide a potential target for molecular therapy. We present a case of ASPS and discuss the histology, diagnostic considerations, cytogenetics, treatment, and prognosis.

Citation

Hinnenkamp G, Hackett A, Grodman B, Primeaux L, Green A, et al. (2022) Alveolar Soft Part Sarcoma: Case Report of a Rare Tumor and Review of Literature. J Surg Oncol Clin Res 4: 4