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Dedifferentiated Chondrosarcoma Developing in Solitary Enchondroma, Case Report of Rare Tumor with Uncommon Presentation and Brief Review of the Literature

[ ISSN : 2473-0688 ]

Abstract
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Received: 01-Feb-2023

Accepted: 20-Feb-2023

Published: 21-Feb-2023

Case Report | Volume 9 - Issue 1 | Article DOI :

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Mohammad Abidali¹*, Graeme Benzie¹, Hassan Abidali², Phillip Pearson³, Deniz Dolun¹, Corey Steinman¹, Jessica Jahoda¹, and Mohamed Aziz⁴

¹American University of the Caribbean Medical School, Dept of Pathology, USA

²Arizona State University, USA

³Philadelphia College of Osteopathic Medicine, Georgia, Dept of Biomedical Sciences, USA

?siParadigm Diagnostic Informatics, NJ, USA

Corresponding Author:

Mohammad Abidali *, Department of Pathology, American University of the Caribbean School of Medicine, AUC, 1 University Drive at Jordan Road Cupecoy, Dutch St. Maarten, USA

Keywords

Dedifferentiated chondrosarcoma; Biphasic; Aggressive; Genetic Alteration.

Abstract

A subtype of aggressive chondrosarcoma known as dedifferentiated chondrosarcoma (DDCS) accounts for about 10% of all chondrosarcomas. The characteristic feature is a low-grade cartilaginous tumor juxtaposed with a high-grade sarcoma with a low 5-year survival rate and a high local recurrence rate. With a 20% 2-year survival rate, DDCS typically strikes older men. There is currently limited literature on the pathogenesis of DDCS, and more investigations are required to improve prognostic factors and treatment options. Our case study’s subject is dedifferentiated chondrosarcoma (DDCS) arising from a single enchondroma. Although it is uncommon, the malignant transformation of a single enchondroma has been documented. Our case already has a pre-existing enchondroma, which supports that DDCS can arise from an enchondroma.

Citation

Abidali M, Benzie G, Abidali H, Pearson P, Dolun D, et al. (2023) Dedifferentiated Chondrosarcoma Developing in Solitary Enchondroma, Case Report of Rare Tumor with Uncommon Presentation and Brief Review of the Literature. SM J Case Rep 9: 5.