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JSM Breast Cancer and Research

Diagnosis of Mammary Paget’s Disease by Cytology Sampling. Case Report and Brief Review of the Literature

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Received: 29-Aug-2023

Accepted: 22-Sep-2023

Published: 26-Sep-2023

Case Report | Volume 4 - Issue 1 | Article DOI :

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Christina Rolquin¹, Madilyn Thomas¹, Meha Munir¹, Victoria DeTrolio¹, Jonathan Nguyen¹, Viviana Crespo¹, Hadel Go², Alan Bencosme³, Jessica Jahoda¹,⁴, and Mohamed Aziz MD⁴*

¹ Department of Pathology, American University of the Caribbean School of Medicine, 1 University Drive at Jordan Dr, Cupecoy, Sint Maarten
² Department of Pathology, Rowan University Medical School, New Jersey, USA
³ Florida Atlantic University, Wilkes Honors College, Florida, USA
? Research Writing & Publication (RWP) LLC, Division of Research, New York, USA

Corresponding Author:

Mohamed Aziz*, Division of Research, Writing & Publication (RWP) LLC, 2475 Lefferts Place Bellmore NY 11710

Abstract

Mammary Paget’s disease (MPD) of the breast is a rare form of breast cancer. It accounts for a very small percentage of breast cancers in women, and much less in men It rarely occurs as an isolated entity and is usually associated with carcinoma in situ or invasive adenocarcinoma in most cases. In situ histology is seen in one third of the cases. Paget’s disease is rarely diagnosed in people under the age of 45. Paget’s disease affects people of all ethnic and racial groups. However, people of Asian descent are less likely to be affected. Surgical treatment of Paget’s disease (radical or conservative) is controversial. There is no established standardized treatment, and treatment decisions are based on other associated conditions. There is currently no evidence that either surgical approach (conservative surgery or mastectomy) improves survival. Prognosis depends on the presence of a palpable mass and the invasiveness of the cancer. We present a case of a 37-year-old woman who presented with recurrent mixed ductal lobular carcinoma associated with Paget’s disease. Paget’s disease diagnosis was completely established based on cytology material sampling only. The patient was treated with bilateral mastectomy with no nipple sparing. The patient was followed for four years with no evidence of metastasis or recurrence.

Citation

Rolquin C, Thomas M, Munir M, DeTrolio V, Nguyen J, et al. (2023) Diagnosis of Mammary Paget’s Disease by Cytology Sampling. Case Report and Brief Review of the Literature. JSM Breast Cancer Res 4: 6.