Keywords
Angiosarcoma, Breast, Primary, High grade
Abstract
Primary angiosarcoma of the breast is uncommon and only diagnosed in roughly 0.04% of all malignant breast tumors. Only 20% of these cases are primary malignancies while the remaining are complications of radiation therapy. Diagnosis is difficult because it tends to mimic benign characteristics on mammogram and histology. Although it can appear benign, breast angiosarcoma is an aggressive, malignant tumor with a poor prognosis. Radiologic imaging along with immunostaining with Factor VIII and CD31 can confirm the presence of angiosarcoma. Currently, surgery is the only treatment option that improves the clinical outcome of the disease, with little help from chemotherapy.
Citation
Weller O, Lubert J, Shirah J, Fernandes K, Furr T, et al. (2022) Primary Angiosarcoma of the Breast: Case Report of Uncommon Tumor and Brief Review of the Literature. JSM Breast Cancer Res 3: 4.