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SM Case Reports

Immunoglobulin A Nephropathy and Prurigo Nodularis Predating the Diagnosis of Hodgkin Lymphoma: A Case Report

[ ISSN : 2473-0688 ]

Abstract
Details

Received: 02-Aug-2017

Accepted: 18-Aug-2017

Published: 22-Aug-2017

Case Report | Volume 3 - Issue 5 | Article DOI :

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Almalki AH¹,²* and Sadagah LF³

¹Consultant Nephrologist and Clinical Epidemiologist, King Abdulaziz Medical City, Saudi Arabia

²Assistant Professor, Medicine and Nephrology, King Saud Bin Abdulaziz University, Saudi Arabia

³Consultant Nephrologist, King Abdulaziz Medical City, Saudi Arabia

Corresponding Author:

Abdullah H Almalki, Section Head, Nephrology, Department of Medicine, King Abdulaziz Medical City, Western Region, P.O. Box 9515 Jeddah 21423, Kingdom of Saudi Arabia, Email: malkia02@ngha.med.sa

Keywords

Immunoglobulin A (IgA) nephropathy; Proteinuria; Prurigonodularis; Hodgkin lymphoma; Lymphoma

Abstract

Background: The association between Hodgkin lymphoma and IgA nephropathy is rarely reported.

Case presentation: A 20-year-old Saudi female patient presented with picture of immunoglobulin A nephropathy and prurigo nodularis. The patient was treated with oral steroid for 6 months; however, by the end of the course, she developed fever, night sweet, and weight loss. Work up was positive for Hodgkin lymphoma involving mediastinal lymph nodes, which was treated with chemotherapy and radiation. Both prurigo nodularis and IgA nephropathy are in complete remission 4 years after cure of lymphoma.

Conclusion: The temporality in presentation and sustained renal remission following lymphoma treatment, may suggest a causal association. Therefore, considering underlying lymphoma in patients with IgA nephropathy may be suggested.

Keywords: Immunoglobulin A (IgA) nephropathy; Proteinuria; Prurigonodularis; Hodgkin lymphoma; Lymphoma

Core tip: The association of IgA nephropathy with Hodgkin’s lymphoma is very rare. In this case report, the temporality and persistent complete remission of proteinuria after lymphoma cure suggest a causal link.

Citation

Almalki AH and Sadagah LF. Immunoglobulin A Nephropathy and Prurigo Nodularis Predating the Diagnosis of Hodgkin Lymphoma: A Case Report. SM J Case Rep. 2017; 3(5): 1057.