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Managing Intracranial Pressure in HIV-associated Cryptococcal Meningitis Saves Lives: Case Report of Two Patients Admitted to a Tanzanian Hospital

[ ISSN : 2473-0688 ]

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Received: 16-Oct-2018

Accepted: 24-Oct-2018

Published: 26-Oct-2018

Case Report | Volume 4 - Issue 3 | Article DOI :

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Rehema H Simbauranga¹*, Sokoine L Kivuyo¹, Sayoki G Mfinanga¹,⁵, Thomas S Harrison², and Rob Peck³,⁴

¹National Institute for Medical Research, Muhimbili Medical Research Centre, Tanzania

²Research Centre for Infection and Immunity, St. George’s University, London

³Center for Global Health, Weill Cornell Medicine, New York, USA

?Weill Bugando School of Medicine, Mwanza, Tanzania

?Muhimbili University of Health and Allied Sciences, United Nations Road, Dar es Salaam, Tanzania

Corresponding Author:

Rehema H Simbauranga, National Institute for Medical Research, Muhimbili Medical Research Centre, Tanzania, Tel: +255 22 2152232; Email: re.he.m@hotmail.com

Keywords

Therapeutic lumbar puncture; Mwananyamala; High fungal burden; Cryptococcal meningitis

Abstract

Cryptococcal meningitis remains a major cause of HIV-related mortality worldwide with majority of cases occurring in sub Saharan Africa. Raised intracranial pressure is a common complication of cryptococcal meningitis and if left untreated is associated with irreversible blindness, deafness and other neurological and neurocognitive impairment. We present two cases which highlight the importance of therapeutic lumbar puncture in the management of raised intracranial pressure in HIV-associated cryptococcal meningitis.

Citation

Simbauranga RH, Kivuyo SL, Mfinanga SG, Harrison TS and Peck R. Managing intracranial pressure in HIV-associated cryptococcal meningitis saves Life: Case report of two patients admitted to a Tanzanian hospital. SM J Case Rep. 2018; 4(3): 1087.