Keywords
Breast cancer; Pure squamous cell carcinoma; Fine needle aspiration cytology
Abstract
SCC is an uncommon and aggressive breast neoplasm. There are limited data in literature about its epidemiology and studies focusing on outcomes, so they are still unclear. It has significantly worse prognosis than other non squamous cell tumors of the breast. Strict histologic criteria should be used to determine diagnosis. Because of its rarity, it is still unclear which the most appropriate therapeutic regimen to use is. The role of different new chemotherapy regimens needs to be explored and biologic studies are needed to determine the tumour chemoresistance mechanisms and the potential use of other treatment targets that improve patients survival. Clinicians should be aware of the aggressive nature of the tumour when counseling patients
Citation
Maurizio M, Carlo C, Paolo D, Silvia B and Eugenio M. Pure Squamous Cell Carcinoma of the Breast: Report Histological Features and Treatment Outcome of Two Cases. SM J Case Rep. 2017; 3(1): 1040.