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SM Journal of Clinical Pathology

Trichoblastic Carcinoma: A Case Report and Literature Review of an Extremely Rare and Diagnostically Challenging Cutaneous Malignancy of the Hair Follicle

[ ISSN : 2576-778X ]

Abstract
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Received: 26-Sep-2020

Accepted: 18-Jan-2038

Published: 17-Oct-2020

Case Report | Volume 4 - Issue 1 | Article DOI :

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Chelsea Azevedo*, Joseph Varney, Karina Leyva, Matthew White, Nicole DiTommaso, Alexandria Kim, Emily Alimia, Cameron Volpe, and Mohamed Aziz

Department of Pathology, American University of the Caribbean, School of Medicine, USA

Corresponding Author:

Chelsea Azevedo, Department of Pathology, American University of the Caribbean School of Medicine, USA, Tel: 916- 899-8895; Email: chelseaazevedo@students.aucmed.edu

Keywords

Trichoblastic, Carcinoma, Cutaneous, Basal cell carcinoma, Stroma, Hair follicle neoplasm. Mitosis

Abstract

Trichoblastic carcinoma (TBC) is an extremely rare cutaneous malignancy of the hair follicle, first described in the literature in 1962 as a “primary neoplasm of the hair matrix” (1). Besides its rarity, TBC shares many clinical and histologic characteristics with basal cell carcinoma (BCC), making the diagnosis of TBC difficult to make. Many authors have described TBC as a malignant transformation of a benign trichoblastoma (TB), but a universal understanding of the pathophysiological origin of TBC has not been established (2, 3). We present a case of this uncommon tumor with the hope that this report will add to the small repertoire of available research, and aid clinicians in diagnosis and management of this rare tumor.

Citation

Azevedo C, Varney J, Leyva K, White M, NDiTommaso M, et al. (2020) Trichoblastic Carcinoma: A Case Report and Literature Review of an Extremely Rare and Diagnostically Challenging Cutaneous Malignancy of the Hair Follicle. SM J Clin Pathol 4: 4.