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SM Case Reports

Unprecedented Brain Imaging Findings in a Case of Acute Disseminated Encephalomyelitis

[ ISSN : 2473-0688 ]

Abstract
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Received: 15-Jan-2016

Accepted: 08-Feb-2016

Published: 10-Feb-2016

Case Report | Volume 2 - Issue 1 | Article DOI :

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Mahale R¹, Mehta A¹, and Rangasetty S¹*

¹ Department of Neurology, MS Ramaiah Medical College & Hospital, India

Corresponding Author:

Rohan R Mahale, Department of Neurology, MS Ramaiah Medical College & Hospital, Bangalore-560054, Karnataka, India

Keywords

Variant; CJD; ADEM; Encephalomyelitis; Pulvinar

Abstract

Acute Disseminated Encephalomyelitis (ADEM) is an acute widespread autoimmune demyelinating disease affecting central nervous system. It is characterized by multifocal white matter lesions on neuroimaging. Grey matter can also be affected, particularly basal ganglia, thalami, and brainstem. Variant Creutzfeldt - Jakob disease (vCJD) is a rare and fatal human neurodegenerative condition affecting younger patients. Pulvinar sign on Magnetic Resonance Imaging (MRI) is considered to be a strong indicator of variant CJD. We report a young patient who presented with febrile illness and altered mental state. Brain imaging revealed hyperintensity in bilateral medial and posterior thalamus. These imaging abnormalities are similar to those seen in variant CJD.

Citation

Mahale R, Mehta A and Rangasetty S. Unprecedented Brain Imaging Findings in a Case of Acute Disseminated Encephalomyelitis. SM J Case Rep. 2016;2(1):1018