Canine anxiety is a widespread behavioural condition that compromises animal welfare and increases the risk of stress related behavioural dysregulation. Severe anxiety disrupts cognitive processing, sleep regulation, and social functioning, often requiring pharmacological support to enable behavioural rehabilitation. This case report describes the clinical response of a 4-year-old Italian Volpino dog with chronic anxiety, hyperarousal, and stress-related dysregulation treated with a micellar CBD formulation (NegEnt). The treatment produced rapid improvements in sleep continuity, arousal modulation, social behaviour, and impulse control without cognitive or motor impairment. Furthermore, a planned temporary discontinuation demonstrated the absence of withdrawal or rebound effects, followed by sustained long-term efficacy over a two-month maintenance period. These observations suggest that micellar CBD may facilitate a “window of cognitive plasticity” that supports behavioural therapy. Controlled studies are required to confirm these preliminary findings.

Although the incidence of gastric cancer has been declining spontaneously and steadily for over 50 years, stomach cancer remains common. The World Health Organization’s 2020 annual report indicates a global incidence of gastric cancer estimated at 1,089,103 new cases per year, representing 5.6% of all cancers, with a mortality rate of approximately 768,793 deaths per year, accounting for 7.7% of all cancer deaths and ranking gastric cancer third in cancer mortality worldwide.

Porcine Reproductive and Respiratory Syndrome (PRRS) causes major economic losses, and cross-protection of Modified-Live Vaccines (MLV) against emerging heterologous strains remains uncertain. This study reports a field based, longitudinal before after intervention study evaluating the impact of a Lineage 7 PRRS MLV (PrimePac® PRRS) during an acute NADC-34 like PRRS outbreak in a commercial 1200-sow farrow-to-finish farm in South Korea. Following a confirmation of an NADC-34 like PRRSV outbreak, a whole-herd mass vaccination program was implemented using intradermal administration (0.2ml) of PrimePac® PRRS. Reproductive performance indicators (farrowing rate, abortions, stillbirths and mummification), vertical transmission dynamics (PRRSV qPCR testing of processing fluids), and post-weaning health outcomes (nursery and grow-finish morbidity and mortality, piglet viremia by qPCR) were monitored longitudinally before and after vaccination. After implementation of the vaccination program, key breeding-herd performance parameters progressively returned toward pre-outbreak baseline levels. PRRSV became undetectable in the processing fluid samples within one month, indicating rapid interruption of vertical transmission. Improvement in nursery and grow-finish pig performance occurred more gradually, consistent with ongoing virus circulation in a continuous-flow production system. This findings demonstrate that, although complete virus elimination was not achieved, a strategic mass vaccination program using a Lineage 7 PRRS MLV substantially mitigated the reproductive and early-life impacts of an NADC-34 like PRRS outbreak. Vaccination combined with biosecurity measures remains a critical component of integrated PRRS control strategies in farrow-to-finish systems where eradication is difficult.

Renal insufficiency is difficult to diagnose in the early stages due to delayed clinical presentation and significant blood value changes. However, dysfunction in the kidneys can lead to life-threatening changes in physiology. When renal insufficiency is suspected, it is important to utilize nutrition as a mode of intervention. This case report follows a canine patient aging between 13 to 17, reporting clinical changes and blood renal values after administration of an NSAID and possible escalation of renal burden. The case outlines an example of utilizing integrative veterinary medicine practices including a home cooked diet plan with supplementation to address signs of renal insufficiency and gastric ulceration, resulting in complete resolution of clinical signs including symptoms and blood measures.

Characterization of goat breeds based on morphological trait variations is essential for planning breed improvement programs and conservation strategies. This study aimed to use multiple correspondence analysis to evaluate qualitative morphological traits and identify traits that best describe the morphological structure of Hararghe goats. The results of the study show that there are significant differences in the distribution of some qualitative morphological traits among the three districts (Bedeno, Fedis, and Gorogutu) while others do not show significant differences. The first principal axis explained 15% of the principal inertia, the second principal axis explained 12%, and cumulatively the first two principal axes explained 27% of the principal inertia. The MCA method identified systematic relationships among traits and trait attributes. On the dimensions identified, the sample goat population of Fedis and Gorogutu clustered together with concave head profile, straight horn shape, obliquely upward horn orientation, presence of Toggle, and pigmented Muzzle; while the corresponding values of goats in Bedeno clustered together with the presence of horn, curved and spiral horn shape, backward and lateral horn and ear orientation with slope down from wither, slope up toward rump, and pendulous. These findings provide valuable information for better multivariate characterization and conservation of indigenous goat ecotypes.

The species Enterococcus saccharolyticus is rarely occurred and identified. No information exists about this species strain bacteriocin/bioactive/postbiotic potential which could be utilized e.g. for bacterial prevention/protection. Standard microbiological methods as well as PCR analyses were used to basic characterization the strain 3/11D27. To test bacteriocin/ postbiotic potential, agar spot test was conducted and 158 indicator bacteria (147 Gram-positive and 11 Gram-negative). The strain E. saccharolyticus Es 3/11D27 was isolated from the inner part of the auricle mucosa of clinically healthy mare (Slovak breed Norik from Murá?) using sequence analysis. After sequencing, the strain was involved in GenBank with accession number MN822909. This strain has produced bacteriocin substance with inhibitory potential against Gram-positive and Gram-negative indicator bacteria non- depending on the indicator bacteria species. The inhibitory activity reached 100 up to 800 AU/ml. Es 3/11D27 has been also susceptible to antibiotics tested. It has been hemolysis-, deoxyribonuclease- negative with absence of virulence factors genes. Low-grade biofilm-forming ability using the plate assay was found in Es 3/11D27. It is first time presenting horses-derived species strain E. saccharolyticus with bacteriocin activity. Additional studies will be processed to determine detail characteristic of bacteriocin substance produced by the strain Es 3/11D27 with the aim for its further application potential in horses breeding.