Background: Anemia remains a significant global public health challenge. However, its prevalence among health professions students residing in high-altitude regions—where physiological adaptations may alter standard hematological parameters—is not well documented. This study aimed to determine the prevalence of anemia and evaluate the complete hematological profiles of medical students at Sana’a University, Yemen, a city situated at approximately 2,250 meters above sea level. Methods: A cross-sectional study was conducted among 100 undergraduate students (51 males and 49 females) aged 19–25 years at the Faculty of Medicine and Health Sciences, Sana’a University. Venous blood samples were collected and analyzed for Complete Blood Count (CBC) parameters using an automated Sysmex XN-330 hematology analyzer. Anemia was initially defined according to the World Health Organization (WHO) sea-level criteria (hemoglobin [Hb]

Results: The overall mean hemoglobin concentration was 15.63 ± 1.73 g/dL. Sex-stratified analysis revealed significantly higher mean Hb levels in males (16.96 ± 1.20 g/dL) compared to females (14.24 ± 0.91 g/dL) (p < 0.001). Other mean hematological indices were as follows: packed cell volume (PCV) 47.05 ± 4.73%, Red Blood Cell (RBC) count 5.43 ± 0.59 × 10¹²/L, Mean Corpuscular Volume (MCV) 86.39 ± 7.63 fL, and Mean Corpuscular Hemoglobin (MCH) 28.82 ± 2.24 pg. Using the unadjusted WHO sea-level criteria, the prevalence of anemia in this cohort was 0%. However, applying the recommended WHO altitude adjustment for Sana’a (+1.0 g/dL) revises the diagnostic thresholds to 14.0 g/dL for males and 13.0 g/dL for females, potentially identifying anemic cases, particularly among female participants. Conclusion: No anemia was detected in this sample of medical students using standard sea-level criteria, a finding likely attributable to high health literacy and physiological adaptation to Sana’a’s altitude. This study highlights the critical need to establish altitude-specific hematological reference ranges for the Yemeni population to prevent the misdiagnosis of anemia in high-altitude regions.

Factor XII deficiency is a rare condition of the coagulation system with autosomal-recessive inheritance. Affected patients are often asymptomatic and are diagnosed incidentally during preoperative investigations or during hospitalization on the basis of an isolated, prolonged activated partial thromboplastin time (aPTT). We report a 39-year-old female who was admitted to hospital for early artificial abortion and abnormal blood coagulation function. We found a novel nonsense mutation (c.247C>T, p. Gln83*) in one of the exon coding regions of the F12 gene on chromosome 5 in a patient with a prolonged aPTT.

Background : Humeral head osteonecrosis is a frequent complication of Sickle Cell Disease (SCD). Little is known about shoulder arthroplasty indications and results in these patients. The aim of this retrospective review is to compare the actual indications and results for SCD to a literature review.

Methods : All shoulder arthroplasties performed on SCD patients between 2016 and 2022 have been evaluated. 17 shoulders in 15 patients were followed up for 2.5 years. Indications, functional and radiological results, and complications were compared to a literature review.

Results : The Constant score significantly improved by 35 points (p =0.016). Patients were finally satisfied with a mean SSV evaluation at 72%. Post-operative complications due to SCD were frequent. There was a bilateral dramatic reverse prosthesis loosening in a patient with severe bone sclerosis due to necrosis. The use of pyrocarbon hemi-arthroplasty is promising and was never described in the literature for SCD shoulder osteonecrosis.

Discussion : Shoulder arthroplasty for collapse humeral head in SCD patients should be considered because of the significant functional improvement that can be obtained. Patients with SCD should be operated in a center with specialized surgeons surrounded by heamatologists to prevent specific complications.

This article provides insights into the current state of social media in the field of hematology-oncology. It highlights the increasing role of platforms like Twitter and Facebook in facilitating information sharing, patient support, and professional collaboration. The article emphasizes the challenges of maintaining accurate reliable content amidst the abundance of information. Additionally, it discusses the potential benefits of social media and fostering patient engagement, clinical trial recruitment, and knowledge dissemination among healthcare professionals and patients.

A 9-year-old boy came to our hospital complaining of headache, vomiting, abdominal pain. Physical examination revealed an increase in submandibular lymph nodes up to 1.5 cm, hepatomegaly.