Abstract
Ulcerative Colitis (UC) is a mucosal disease that usually involves the rectum and extends proximally to involve all or part of the colon. Main causes are gut microbiota, dysregulation of the host’s immune system, genetic susceptibility and environmental factors. Active disease can be associated with a rise in acute phase reactants [C - reactive protein (CRP)], platelet count and Erythrocyte Sedimentation Rate (ESR) and a decrease in hemoglobin. Colonoscopy is used to assess disease activity and is often performed before treatment. In this case, recurrence UC was observed and it was treated with suitable therapy but some drug interactions like metronidizole additive effect with ofloxacin results in ST-T elevation and adverse effects like abdominal pain, burning pain in midsternal area radiating to epigastric region [Calcium+Vitamin-D] were seen. Those are monitored by the alternative therapy like dose management and drug alterations.
Citation
Sandeep RJ, Hari HC, Jyothsna RD and Mahender V. A Case Report on Ulcerative Colitis with Interventional Outcomes. J Gastroenterol. 2016; 2(1): 1004.