Abstract
Background and Aim: There is an increasing concern on Post-Colonoscopy Colorectal Carcinomas (PostCRCs). Little is known about how these figures have evolved over time. We aim to compare the rates of PostCRCs in two periods of time and identify the risk factors.
Methods: Retrospective control-case study in our Endoscopic Unit. We studied two separate intervals (March 2004-September 2011 and October 2011 - December 2016). In both periods of time all patients diagnosed with CRC were identified. Patients with a previous colonoscopy performed 12 to 60 months before were retrieved (cases) and compared with those who did not have a previous procedure (controls).
Results: 712 and 743 patients diagnosed with CRC in both periods of time. 24 patients in the first period (3.6%) and 28 patients in the second one (3.8%) had a previous colonoscopy performed. PostCRCs were mainly located on the right side of the colon (63% vs. 35% p=0.006 and 68% vs. 33% p< 0.001), were smaller in size (3.17 vs.4.46 p< 0.001 and 3.61 vs. 4.44 p=0.086), with a tendency to host a better TNM stage. No differences in sex and age were found.
More than half of PostCRCs (58.3% and 60.7%) were attributed to procedure causes, meanwhile10 PostCRCs in both periods were considered new developed CRCs.
Conclusions: Despite what could be expected, we did not find a decrease in the rate of PostCRCs over time. A combination of preventable as much as biological factors would account for their etiology.
Citation
Rebollo MLR and Moreno MFM. Post-Colonoscopy Colorectal Carcinomas (PostCRCs): Have we Improved Over Time? J Gastroenterol. 2017; 3(2): 1010.