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SM Journal of Gastroenterology & Hepatology

Recurrent Gastrointestinal Stromal Tumor of the Small Intestine with Malignant Features: A Case Report of Uncommon Tumor and Review of the Literature

[ ISSN : 3067-977X ]

Abstract
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Received: 03-Mar-2021

Accepted: 22-Mar-2021

Published: 23-Mar-2021

Case Report | Volume 5 - Issue 1 | Article DOI :

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Kiley Clark*, Morgan Sly, Jamie Spears, Gabriela Morales, Nicole Forte, Iqra Bhatti, and Mohamed Aziz

Department of Pathology- American University of the Caribbean, School of Medicine, USA

Corresponding Author:

Kiley Clark, Department of Pathology, American University of the Caribbean School of Medicine, 1 University Drive at Jordan Road Cupecoy, St. Maarten, Tel: (916) 241-6746; Email: kileyclark@students.aucmed.edu

Keywords

Stromal; Malignant; Recurrence; Necrosis; Imatinib

Abstract

Gastrointestinal (GI) stromal tumors (GISTs), although rare, are the most common mesenchymal tumor of the GI tract. They comprise approximately 80% of all GI mesenchymal tumors and most commonly occur in the stomach and small bowel1. GISTs originate from interstitial cells of cajal (ICCs), mesenchymal cells located within the muscular layer of the GI tract, which generate electrical pacemaker activity for gut motility. These cells express the KIT protein on their cell surface, and GIST almost universally stain positive for the KIT protein by immunohistochemical staining. We present a case of this uncommon tumor and review the literature.

Citation

Clark K, Sly M, Spears J, Morales G, Forte N, et al. (2021) Recurrent Gastrointestinal Stromal Tumor of the Small Intestine with Malignant Features: A Case Report of Uncommon Tumor and Review of the Literature. SM J Gastroenterol Hepatol 5: 4.