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SM Journal of Cardiology and Cardiovascular Diseases

Role of Neutrophils in the Inflammation of Brain

[ ISSN : 3068-0034 ]

Abstract
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Received: 08-Aug-2017

Accepted: 11-Aug-2017

Published: 16-Aug-2017

Short Communication | Volume 3 - Issue 2 | Article DOI :

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Tarik Kivrak1*, Mehmet Balin1, Mehmet Ali Kobalt1 and Emrah Aytac Ilgin Karaca2

1Department of Cardiology, Firat University Hospital, Elazig, Turkey

2Department of Neurology, Firat University Hospital, Elazig, Turkey

Corresponding Author:

Tarik Kivrak, Department of Cardiology, Firat University Hospital, Elazig, Turkey, Tel: 05053729945

Keywords

Inflammation; Neutrophils; Stroke

Abstract

The immune response after stroke is known to play a significant role in ischemic brain. The inflammatory messages let out by immune contacts activated by brain damage sets off a complex series of pathologic events which have been progressively recognized as an essential attendant to neuronal death. The primary immune mediators contained are glial cells and infiltrating leukocytes, including neutrophils, monocytes, and lymphocyte. After ischemic stroke, infiltrated leukocytes release inflammatory mediators into the site of the lesion, thereby exacerbating brain injury. This review describes how the roles of circulating neutrophils are a double-edged sword for neuroinflammation by focusing on their detrimental and protective effects in ischemic stroke. Here, we will concentrate on underlying characterize of glial cells and leukocytes under inflammation after ischemic stroke.

Citation

Kivrak T, Balin M, Kobalt MA and Karaca EAI. Role of Neutrophils in the Inflammation of Brain. SM J Cardiolog and Cardiovasc Disord. 2017; 3(2): 1011s1.